{"id":4804,"date":"2022-01-28T10:54:00","date_gmt":"2022-01-28T03:54:00","guid":{"rendered":"http:\/\/benhvienhuyencuchi.com\/?p=4804"},"modified":"2023-03-09T10:39:36","modified_gmt":"2023-03-09T03:39:36","slug":"lien-quan-giua-nhom-mau-va-muc-do-nghiem-trong-khi-mac-covid-19","status":"publish","type":"post","link":"https:\/\/benhvienhuyencuchi.com\/?p=4804","title":{"rendered":"Li\u00ean quan gi\u1eefa nh\u00f3m m\u00e1u v\u00e0 m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng khi m\u1eafc COVID-19<\/a>"},"content":{"rendered":"\n\n\n

K\u1ec3 t\u1eeb khi virus SARS-CoV-2 xu\u1ea5t hi\u1ec7n, khi\u1ebfn nhi\u1ec1u ng\u01b0\u1eddi nhi\u1ec5m tr\u1edf n\u1eb7ng v\u00e0 t\u1eed vong, c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 n\u1ed7 l\u1ef1c nghi\u00ean c\u1ee9u v\u00e0 \u0111i t\u00ecm l\u1eddi gi\u1ea3i cho c\u00e2u h\u1ecfi li\u1ec7u nh\u00f3m m\u00e1u c\u00f3 li\u00ean quan \u0111\u1ebfn m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng khi m\u1eafc COVID-19 hay kh\u00f4ng.<\/p>\n

Ph\u00e1t hi\u1ec7n m\u1edbi \u0111\u00e2y c\u1ee7a c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u thu\u1ed9c \u0110\u1ea1i h\u1ecdc King’s College London \u0111\u01b0\u1ee3c cho l\u00e0 c\u00f3 th\u1ec3 cung c\u1ea5p c\u00e1c ph\u01b0\u01a1ng ph\u00e1p ti\u1ebfp c\u1eadn ti\u1ec1m n\u0103ng m\u1edbi \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb v\u00e0 ng\u0103n ng\u1eeba c\u00e1c tr\u01b0\u1eddng h\u1ee3p m\u1eafc COVID-19 nghi\u00eam tr\u1ecdng nh\u1ea5t.<\/p>\n

\u0110i t\u00ecm l\u1eddi gi\u1ea3i cho c\u00e2u h\u1ecfi tr\u00ean, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u thu\u1ed9c \u0110\u1ea1i h\u1ecdc King’s College London \u0111\u00e3 ph\u00e2n t\u00edch h\u01a1n 3.000 protein \u0111\u1ec3 xem li\u1ec7u c\u00f3 m\u1ed1i li\u00ean quan n\u00e0o v\u1edbi nguy c\u01a1 COVID-19 di\u1ec5n ti\u1ebfn n\u1eb7ng. \u0110\u00e2y l\u00e0 l\u1ea7n \u0111\u1ea7u ti\u00ean m\u1ed9t l\u01b0\u1ee3ng l\u1edbn protein nh\u01b0 v\u1eady \u0111\u01b0\u1ee3c xem x\u00e9t \u0111\u1ec3 t\u00ecm m\u1ed1i li\u00ean h\u1ec7 v\u1edbi COVID-19.<\/p>\n

Cho \u0111\u1ebfn nay, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u00e3 x\u00e1c \u0111\u1ecbnh \u0111\u01b0\u1ee3c t\u00e1m lo\u1ea1i protein c\u00f3 th\u1ec3 b\u1ea3o v\u1ec7 ch\u1ed1ng l\u1ea1i COVID-19 di\u1ec5n ti\u1ebfn n\u1eb7ng v\u00e0 s\u00e1u lo\u1ea1i protein c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 m\u1eafc COVID-19 n\u1eb7ng.<\/p>\n

ABO – m\u1ed9t trong nh\u1eefng protein l\u00e0m t\u0103ng nguy c\u01a1 di\u1ec5n ti\u1ebfn n\u1eb7ng, c\u0169ng quy\u1ebft \u0111\u1ecbnh nh\u00f3m m\u00e1u c\u1ee7a con ng\u01b0\u1eddi. Ti\u1ebfn s\u1ef9 Alish Palmos, \u0111\u1ed3ng t\u00e1c gi\u1ea3 nghi\u00ean c\u1ee9u cho bi\u1ebft \u0111\u00e3 c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 s\u1eed d\u1ee5ng ph\u01b0\u01a1ng ph\u00e1p di truy\u1ec1n thu\u1ea7n t\u00fay \u0111\u1ec3 xem x\u00e9t m\u1ed9t l\u01b0\u1ee3ng l\u1edbn c\u00e1c protein trong m\u00e1u, \u0111\u1ed3ng th\u1eddi x\u00e1c \u0111\u1ecbnh r\u1eb1ng m\u1ed9t s\u1ed1 \u00edt protein c\u00f3 m\u1ed1i li\u00ean quan \u0111\u1ebfn nguy c\u01a1 m\u1eafc COVID-19 n\u1eb7ng.<\/p>\n

B\u00ean c\u1ea1nh \u0111\u00f3, c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 t\u00ecm th\u1ea5y t\u00e1m lo\u1ea1i protein c\u00f3 th\u1ec3 ch\u1ed1ng l\u1ea1i nguy c\u01a1 nh\u1eadp vi\u1ec7n, nguy c\u01a1 ph\u1ea3i d\u00f9ng m\u00e1y tr\u1ee3 th\u1edf ho\u1eb7c t\u1eed vong v\u00e0 s\u00e1u lo\u1ea1i protein l\u00e0m t\u0103ng nh\u1eefng nguy c\u01a1 \u0111\u00f3. C\u00e1c nh\u00e0 khoa h\u1ecdc th\u1eadm ch\u00ed c\u00f2n ph\u00e2n bi\u1ec7t gi\u1eefa c\u00e1c protein li\u00ean quan \u0111\u1ebfn nh\u1eadp vi\u1ec7n v\u1edbi c\u00e1c protein li\u00ean quan \u0111\u1ebfn vi\u1ec7c b\u1ec7nh nh\u00e2n c\u1ea7n ph\u1ea3i th\u1edf m\u00e1y.<\/p>\n

Do \u0111\u00f3, c\u00e1c nh\u00e0 khoa h\u1ecdc k\u1ebft lu\u1eadn enzyme ABO, x\u00e1c \u0111\u1ecbnh nh\u00f3m m\u00e1u, c\u00f3 li\u00ean quan \u0111\u1ebfn vi\u1ec7c t\u0103ng nguy c\u01a1 nh\u1eadp vi\u1ec7n v\u00e0 ph\u1ea3i s\u1eed d\u1ee5ng thi\u1ebft b\u1ecb tr\u1ee3 th\u1edf. \u0110i\u1ec1u n\u00e0y c\u1ee7ng c\u1ed1 nh\u1eefng ph\u00e1t hi\u1ec7n tr\u01b0\u1edbc \u0111\u00e2y v\u1ec1 m\u1ed1i li\u00ean h\u1ec7 gi\u1eefa nh\u00f3m m\u00e1u v\u1edbi nguy c\u01a1 t\u1eed vong cao h\u01a1n.<\/p>\n

Nh\u1eefng ng\u01b0\u1eddi c\u00f3 nh\u00f3m m\u00e1u A c\u00f3 t\u1ef7 l\u1ec7 d\u01b0\u01a1ng t\u00ednh v\u1edbi virus SARS-CoV-2 cao h\u01a1n, n\u00ean c\u00e1c nh\u00e0 khoa h\u1ecdc cho r\u1eb1ng c\u1ea7n kh\u1ea3o s\u00e1t nh\u00f3m m\u00e1u n\u00e0y.<\/p>\n

Gi\u00e1o s\u01b0 Gerome Breen, \u0111\u1ed3ng t\u00e1c gi\u1ea3 nghi\u00ean c\u1ee9u v\u00e0 l\u00e0 Gi\u00e1o s\u01b0 Di truy\u1ec1n h\u1ecdc thu\u1ed9c \u0110\u1ea1i h\u1ecdc King’s College London kh\u1eb3ng \u0111\u1ecbnh nghi\u00ean c\u1ee9u tr\u00ean cung c\u1ea5p m\u1ed9t danh s\u00e1ch r\u00fat g\u1ecdn cho giai \u0111o\u1ea1n nghi\u00ean c\u1ee9u ti\u1ebfp theo.<\/p>\n

C\u1ee5 th\u1ec3, trong s\u1ed1 h\u00e0ng ngh\u00ecn lo\u1ea1i protein trong m\u00e1u, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u00e3 r\u00fat g\u1ecdn c\u00f2n kho\u1ea3ng 14 lo\u1ea1i c\u00f3 m\u1ed1i li\u00ean quan \u0111\u1ebfn nguy c\u01a1 m\u1eafc COVID-19 n\u1eb7ng, \u0111\u1ed3ng th\u1eddi v\u1ea1ch ra h\u01b0\u1edbng \u0111i quan tr\u1ecdng cho c\u00e1c nghi\u00ean c\u1ee9u ti\u1ebfp theo s\u00e2u h\u01a1n, \u0111\u1ec3 hi\u1ec3u r\u00f5 h\u01a1n v\u1ec1 c\u01a1 ch\u1ebf c\u1ee7a c\u0103n b\u1ec7nh n\u00e0y, v\u1edbi m\u1ee5c \u0111\u00edch cu\u1ed1i c\u00f9ng l\u00e0 ph\u00e1t tri\u1ec3n c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb m\u1edbi c\u0169ng nh\u01b0 c\u00e1c bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba.<\/p>\n

Ngo\u00e0i ra, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u c\u0169ng t\u00ecm ra ba ph\u00e2n t\u1eed “li\u00ean k\u1ebft” l\u00e0m trung gian t\u01b0\u01a1ng t\u00e1c gi\u1eefa c\u00e1c t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch v\u00e0 m\u1ea1ch m\u00e1u, c\u00f3 li\u00ean quan \u0111\u1ebfn vi\u1ec7c gi\u1ea3m nguy c\u01a1 nh\u1eadp vi\u1ec7n. \u0110i\u1ec1u n\u00e0y ph\u00f9 h\u1ee3p v\u1edbi nghi\u00ean c\u1ee9u tr\u01b0\u1edbc \u0111\u00e2y cho th\u1ea5y COVID-19 giai \u0111o\u1ea1n cu\u1ed1i l\u00e0 c\u0103n b\u1ec7nh li\u00ean quan \u0111\u1ebfn ni\u00eam m\u1ea1c c\u1ee7a m\u1ea1ch m\u00e1u.<\/p>\n

\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":4,"featured_media":4805,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[1,2],"tags":[],"_links":{"self":[{"href":"https:\/\/benhvienhuyencuchi.com\/index.php?rest_route=\/wp\/v2\/posts\/4804"}],"collection":[{"href":"https:\/\/benhvienhuyencuchi.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/benhvienhuyencuchi.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/benhvienhuyencuchi.com\/index.php?rest_route=\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/benhvienhuyencuchi.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4804"}],"version-history":[{"count":0,"href":"https:\/\/benhvienhuyencuchi.com\/index.php?rest_route=\/wp\/v2\/posts\/4804\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/benhvienhuyencuchi.com\/index.php?rest_route=\/wp\/v2\/media\/4805"}],"wp:attachment":[{"href":"https:\/\/benhvienhuyencuchi.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4804"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/benhvienhuyencuchi.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=4804"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/benhvienhuyencuchi.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=4804"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}